The Genomic and Transcriptomic Landscape of Plasma Cell Leukemia
نویسندگان
چکیده
منابع مشابه
The Genomic and Transcriptomic Landscape of a HeLa Cell Line
HeLa is the most widely used model cell line for studying human cellular and molecular biology. To date, no genomic reference for this cell line has been released, and experiments have relied on the human reference genome. Effective design and interpretation of molecular genetic studies performed using HeLa cells require accurate genomic information. Here we present a detailed genomic and trans...
متن کاملGenomic and transcriptomic landscape of Escherichia coli BL21(DE3)
Escherichia coli BL21(DE3) has long served as a model organism for scientific research, as well as a workhorse for biotechnology. Here we present the most current genome annotation of E. coli BL21(DE3) based on the transcriptome structure of the strain that was determined for the first time. The genome was annotated using multiple automated pipelines and compared to the current genome annotatio...
متن کاملGenomic and transcriptomic sequencing in chronic lymphocytic leukemia
Cortese, D. 2016. Genomic and transcriptomic sequencing in chronic lymphocytic leukemia. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1259. 63 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9702-6. Identification of recurrent mutations through next-generation sequencing (NGS) has given us a deeper understanding of the molecular mechanisms i...
متن کاملThe genomic landscape of chronic lymphocytic leukemia: clinical implications
A precise understanding of the genomic and epigenomic features of chronic lymphocytic leukemia (CLL) may benefit the study of the disease's staging and treatment. While recent reports have shed some light on these aspects, several challenges need to be addressed before translating this research into clinical practice. Thus, even the best candidate driver genes display low mutational rates compa...
متن کاملTranscriptomic landscape of the primitive streak.
In birds and mammals, all mesoderm cells are generated from the primitive streak. Nascent mesoderm cells contain unique dorsoventral (D/V) identities according to their relative ingression position along the streak. Molecular mechanisms controlling this initial phase of mesoderm diversification are not well understood. Using the chick model, we generated high-quality transcriptomic datasets of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2020
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2020-139340